Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440618 | 0.86 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL1475607 | 0.83 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2PAX8MAPT | |
| SCHEMBL15956268 | 0.81 | ALDH1A1 (0.80) | ALDH1A1LMNASMN1; SMN2PAX8MAPT | |
| SCHEMBL24629449 | 0.75 | ALDH1A1 (0.78) | ALDH1A1LMNASMN1; SMN2PAX8MAPT | |
| SCHEMBL29937693 | 0.74 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2MAPTSLC6A5 | |
| SCHEMBL7800482 | 0.74 | GAA (0.72) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL2103553 | 0.74 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2MAPTSLC6A5 | |
| SCHEMBL34475293 | 0.73 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2PAX8MAPT | |
| SCHEMBL6506814 | 0.73 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2PAX8MAPT | |
| SCHEMBL2390332 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2MAPTSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11080141-A | — | — | None | — | — | JP | disclosed |
| JP-11079998-A | — | — | None | — | — | JP | disclosed |
| JP-H1180141-A | DIPHENYL COMPOUND | DAI ICHI SEIYAKU CO LTD | 1999-03-26 | — | — | JP | disclosed |
| JP-H1179998-A | ANTITUMOR AGENT | DAI ICHI SEIYAKU CO LTD | 1999-03-23 | — | — | JP | disclosed |