Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103553 | 1.00 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL6815260 | 0.85 | GAA (0.69) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL3920380 | 0.85 | SLC6A5 (0.86) | ALDH1A1MAPTSMN1; SMN2SLC6A9SLC6A5 | |
| SCHEMBL7800482 | 0.84 | GAA (0.72) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL6811691 | 0.84 | GAA (0.71) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL2061743 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL1026363 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL210786 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL3252577 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2388988 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215816-B | Synthesis method of lactam compound | 普济生物科技（台州）有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-115215816-A | Synthesis method of lactam compound | 普济生物科技（台州）有限公司 | 2022-10-21 | — | — | CN | disclosed |
| WO-2022218348-A1 | METHOD FOR SYNTHESIZING LACTAM COMPOUNDS | Seasons Biotechnology (Taizhou) Co., Ltd. (CN) | 2022-10-20 | — | — | WO | disclosed |