Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549722 | 0.85 | HRH3 (0.41) | GPBAR1 | |
| SCHEMBL27479451 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL20971533 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8438266 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8438262 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8442091 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8439673 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL20971523 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8522255 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 | |
| SCHEMBL8772526 | 0.83 | PLAAT3 (0.47) | ALDH1A1POLBLMNAPLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990102-A | Substituted azetidin-2-ones for treatment of atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-11-23 | — | — | US | claimed |