Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439074 | 0.84 | ALDH1A1 (0.67) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL15503676 | 0.76 | MEN1 (0.64) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL15503679 | 0.73 | MEN1 (0.59) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL15503673 | 0.71 | KMT2A (1.00) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11571324 | 0.70 | ATM (0.45) | RAB9ANPC1ALDH1A1HPGDLMNA | |
| SCHEMBL15507853 | 0.69 | MEN1 (0.52) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL21316220 | 0.68 | KMT2A (0.74) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL15503668 | 0.67 | RAB9A (0.52) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11544407 | 0.67 | MAPT (0.50) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL11683297 | 0.67 | ALDH1A1 (0.68) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640597-A1 | Acylamino substituted isoxazoles and/or isothiazols, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1995-03-01 | — | — | EP | claimed |
| EP-0640597-B1 | Acylamino substituted isoxazoles and/or isothiazols, process for their preparation and their use | BASF AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| US-5538939-A | HERBICIDES AND PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |
| EP-0640597-A1 | Acylamino substituted isoxazoles and/or isothiazols, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1995-03-01 | — | — | EP | disclosed |
| EP-0640597-A1 | Acylamino substituted isoxazoles and/or isothiazols, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1995-03-01 | — | — | EP | disclosed |