Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000951 | 0.86 | LTA4H (0.41) | KIF11ALDH1A1HDAC1HDAC2 | |
| SCHEMBL10779500 | 0.83 | LTA4H (0.52) | CA1CA2CA9HDAC1HDAC2 | |
| SCHEMBL18293362 | 0.82 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL306823 | 0.82 | KIF11 (0.50) | KIF11HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7988345 | 0.80 | KIF11 (0.41) | KIF11CA1CA2CA9ALDH1A1 | |
| SCHEMBL28910204 | 0.80 | SERPINE1 (0.49) | KIF11HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL27629692 | 0.79 | KIF11 (0.34) | KIF11CA9AURKATPX2SCN5A | |
| SCHEMBL7970585 | 0.78 | KIF11 (0.46) | KIF11CA1CA2CA9ALDH1A1 | |
| SCHEMBL8370351 | 0.78 | KIF11 (0.46) | KIF11CA1CA2CA9ALDH1A1 | |
| SCHEMBL2088413 | 0.77 | PPARG (0.33) | SERPINE1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998667-A | CHEMICAL INTERMEDIATE FOR INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| US-5807877-A | Substituted biphenyl oxazolines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0784617-A1 | SUBSTITUTED DIPHENYL OXAZOLINES | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011190-A1 | SUBSTITUTED DIPHENYL OXAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-18 | — | — | WO | disclosed |