Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005080 | 0.83 | KMT2A (0.51) | HPGDKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30418900 | 0.83 | TMEM97 (0.57) | HPGDKMT2ASMN1; SMN2ALDH1A1TMEM97 | |
| Hydrochloric Acid SCHEMBL7995813 | 0.83 | KMT2A (0.50) | HPGDKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8444019 | 0.82 | CA12 (0.54) | HPGDKMT2ASMN1; SMN2ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL8004278 | 0.82 | SMN1; SMN2 (0.47) | HPGDKMT2ASMN1; SMN2ALDH1A1TMEM97 | |
| SCHEMBL8440438 | 0.81 | TSHR (0.46) | HPGDALDH1A1MAPTCYP1A2LMNA | |
| SCHEMBL8440765 | 0.81 | MAPK1 (0.45) | HPGDKMT2ASMN1; SMN2ALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL8663971 | 0.81 | KMT2A (0.51) | HPGDKMT2ASMN1; SMN2MEN1GAA | |
| Hydrochloric Acid SCHEMBL8442851 | 0.81 | MAPK1 (0.41) | HPGDKMT2ASMN1; SMN2ALDH1A1TMEM97 | |
| SCHEMBL8440378 | 0.80 | ALDH1A1 (0.60) | HPGDKMT2ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |