Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444450 | 0.89 | TNKS (0.40) | CYP1A1CYP1A2CYP1B1MAPTSMN1; SMN2 | |
| SCHEMBL8442957 | 0.83 | CHRM2 (0.49) | SMN1; SMN2HTTCHRM2CHRM4CHRM5 | |
| SCHEMBL8441352 | 0.78 | FYN (0.41) | CYP1A2HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL21817675 | 0.76 | CYP4F2 (0.44) | CYP4F2CYP4A11LOXL2TSHRHPGD | |
| SCHEMBL2409006 | 0.75 | CYP4F2 (0.43) | CYP4F2CYP4A11LOXL2MAPTSMN1; SMN2 | |
| SCHEMBL7824090 | 0.73 | EGFR (0.52) | CYP4F2CYP4A11LOXL2MAPTTSHR | |
| SCHEMBL8442873 | 0.73 | KEAP1 (0.43) | MAPTSMN1; SMN2THRBTSHRHPGD | |
| SCHEMBL21819238 | 0.72 | MKNK1 (0.49) | CYP4F2CYP4A11LOXL2SMN1; SMN2HPGD | |
| SCHEMBL21818278 | 0.72 | PPARG (0.46) | CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL3477961 | 0.72 | ESR2 (0.42) | CYP4F2CYP4A11LOXL2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |