Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | PGK1 | P00558 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986241 | 0.83 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL10102084 | 0.83 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL11465165 | 0.82 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDMAPK8 | |
| SCHEMBL11326931 | 0.81 | MAPK8 (0.51) | KDM4EHSD17B10ALDH1A1HPGDPGK1 | |
| SCHEMBL14004275 | 0.79 | AURKA (0.46) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL14004274 | 0.76 | AURKA (0.44) | KDM4EHSD17B10ALDH1A1HPGDMAPK8 | |
| SCHEMBL8442022 | 0.75 | L3MBTL1 (0.48) | KDM4EHSD17B10ALDH1A1HPGDPGK1 | |
| SCHEMBL31384575 | 0.75 | ALDH1A1 (0.74) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL9956692 | 0.75 | ALDH1A1 (0.74) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL29496331 | 0.74 | L3MBTL1 (0.57) | KDM4EHSD17B10ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688318-B1 | PROCESS FOR PRODUCING DIAMINO PYRIDINES | BASF AG (DE) | 1999-02-17 | — | — | EP | disclosed |
| US-5536840-A | AMINATION OF DICHLOROPYRIDINE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-16 | — | — | US | disclosed |
| EP-0688318-A1 | PROCESS FOR PRODUCING DIAMINO PYRIDINES | BASF Aktiengesellschaft (DE) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020469-A1 | PROCESS FOR PRODUCING DIAMINO PYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-15 | — | — | WO | disclosed |