Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023262 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP2C19LMNACYP2D6KMT2A | |
| SCHEMBL15338471 | 0.81 | MEN1 (0.54) | ALDH1A1CYP2C19LMNACYP2D6KMT2A | |
| SCHEMBL28102384 | 0.80 | MEN1 (0.52) | ALDH1A1CYP2C19LMNACYP2D6KMT2A | |
| SCHEMBL194549 | 0.80 | MEN1 (0.52) | ALDH1A1CYP2C19LMNAKMT2AMEN1 | |
| SCHEMBL11756979 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP2C19LMNAKMT2AMEN1 | |
| SCHEMBL11216066 | 0.77 | MEN1 (0.62) | ALDH1A1CYP2C19LMNACYP2D6KMT2A | |
| SCHEMBL3231208 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL30819194 | 0.74 | MMP1 (0.61) | KMT2AMEN1CYP3A4MAPTTDP1 | |
| SCHEMBL4021293 | 0.74 | ALDH1A1 (1.00) | ALDH1A1CYP2C19LMNACYP2D6TAAR1 | |
| SCHEMBL4021288 | 0.74 | ALDH1A1 (1.00) | ALDH1A1CYP2C19LMNACYP2D6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758314-B1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LTD (GB) | 1999-09-15 | — | — | EP | claimed |
| EP-0758314-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | Vanguard Medica Limited (GB) | 1997-02-19 | — | — | EP | claimed |
| WO-1995030646-A1 | COMPOUNDS CONTAINING A MICHAEL-ACCEPTOR, ESPECIALLY MALEIMIDE OR MALEIC ACID DERIVATIVES, DIRECTLY OR INDIRECTLY LINKED TO A CHROMOPHORE AND THEIR USE IN LONG LASTING SUNSCREEN COMPOSITIONS | VANGUARD MEDICA LIMITED (GB) | 1995-11-16 | — | — | WO | claimed |