Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22905235 | 0.79 | TRPA1 (0.37) | TRPA1HCAR2MPOGRIN1GRIN2B | |
| SCHEMBL11966190 | 0.77 | ALDH1A1 (0.36) | FDPSGPR55 | |
| SCHEMBL28095950 | 0.76 | — | — | |
| SCHEMBL7912506 | 0.75 | DAO (0.46) | GRIN1GRIN2BFDPSGPR55 | |
| SCHEMBL8438131 | 0.75 | CYP11B1 (0.38) | HCAR2GRIN1GRIN2BFDPSGPR55 | |
| SCHEMBL19182714 | 0.75 | IDO1 (0.36) | GRIN2BCHRNA4 | |
| SCHEMBL1864498 | 0.75 | TSHR (0.42) | GRIN2BCHRNA4 | |
| SCHEMBL3643700 | 0.73 | — | — | |
| SCHEMBL9645885 | 0.71 | — | — | |
| SCHEMBL693319 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |