Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600311 | 0.80 | KDM4E (0.58) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| (+)-Oxypeucedanin SCHEMBL28392858 | 0.78 | ALDH1A1 (0.61) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL9361777 | 0.77 | ALDH1A1 (0.56) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL23640376 | 0.76 | KDM4E (0.57) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL4795310 | 0.76 | PTPN1 (0.53) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL2583433 | 0.75 | KCNA3 (0.65) | KCNA2KCNA3THRBKCNA5 | |
| Psoralen SCHEMBL28497870 | 0.74 | KDM4E (0.86) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL28145934 | 0.74 | MAOA (0.54) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL1301705 | 0.74 | CYP3A4 (0.62) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 | |
| SCHEMBL18073930 | 0.73 | AKR1B1 (0.61) | PTPN1CYP3A4KDM4EHSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579784-B1 | METHOD FOR PREVENTING RESTENOSIS FOLLOWING RECONFIGURATION OF BODY VESSELS | ADVANCED RES & TECH INST (US) | 1999-11-10 | — | — | EP | claimed |
| US-5405868-A | Treating skin disorders | GOUPIL JEAN-JACQUES (FR) | 1995-04-11 | — | — | US | disclosed |
| US-5360816-A | ORALLY ADMINISTERING 5-METHOXY-PSORALEN TO A PATIENT AND THEN EXPOSING PATIENT TO ULTRAVIOLET RADIATION | GOUPIL JEAN JACQUES (FR) | 1994-11-01 | — | — | US | disclosed |
| US-4429138-A | MULTISTEP, FROM PHLOROGLUCINOL | GOUPIL JEAN JACQUES (FR) | 1984-01-31 | — | — | US | disclosed |