Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913212 | 0.79 | MAPT (0.52) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL10913217 | 0.79 | MAPT (0.52) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL10913222 | 0.79 | MAPT (0.52) | CYP1A2CYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL8443291 | 0.74 | ABCC9 (0.41) | ABCC9 | |
| SCHEMBL2009843 | 0.73 | IDO1 (0.40) | ABCB1IDO1ABCC9 | |
| Hydrochloric Acid SCHEMBL2883645 | 0.72 | IDO1 (0.39) | ABCB1IDO1ABCC9 | |
| SCHEMBL9589780 | 0.71 | ABCC9 (0.35) | ABCB1ABCC9 | |
| SCHEMBL9591149 | 0.69 | ABCC9 (0.35) | ABCB1ABCC9 | |
| SCHEMBL9685744 | 0.67 | KCNA5 (0.42) | SMN1; SMN2MAPTABCC9 | |
| SCHEMBL9685762 | 0.67 | KCNA5 (0.42) | SMN1; SMN2MAPTABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919806-A | 8-AMINOPYRANO(2.3-F)BENZO-OXADIAZOLES, THIADIAZOLES AND TRIAZOLES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-06 | — | — | US | disclosed |
| EP-0693283-A1 | HEART FAILURE REMEDY | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |