Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361291 | 0.78 | KLK7 (0.54) | CYP1A2 | |
| SCHEMBL361290 | 0.78 | KLK7 (0.54) | CYP1A2 | |
| SCHEMBL10407749 | 0.78 | SRR (0.59) | SRRPPARGPPARAACE | |
| SCHEMBL20979753 | 0.77 | MME (0.50) | SRRPPARGPPARAACEMME | |
| SCHEMBL19846395 | 0.75 | IL1RN (0.44) | SRRANPEPRNPEPDNPEPPPARG | |
| SCHEMBL517463 | 0.75 | ALDH1A1 (0.60) | ANPEPHPGD | |
| SCHEMBL2600694 | 0.75 | ALDH1A1 (0.60) | ANPEPHPGD | |
| SCHEMBL17761604 | 0.75 | ALDH1A1 (0.60) | ANPEPHPGD | |
| SCHEMBL9800444 | 0.75 | KLK7 (0.47) | — | |
| SCHEMBL7310650 | 0.75 | ALDH1A1 (0.51) | ANPEPPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869786-A4 | PHARMACEUTICAL COMPOUNDS | LILLY CO ELI (US) | 1999-04-14 | — | — | EP | disclosed |
| EP-0869786-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023211-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |