SCHEMBL8440952

SCHEMBL8440952

CS(=O)(=O)ONC(N)=NC(=O)c1cccc(-c2c(Cl)sc3ccccc23)c1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8443930 0.86 SLC9A1 (0.40) SLC9A1
SCHEMBL8443921 0.81 HTR2B (0.39) SLC9A1
SCHEMBL8440927 0.80 HDAC2 (0.46) SLC9A1
SCHEMBL8440628 0.80 SLC9A1 (0.40) SLC9A1
SCHEMBL7822730 0.79 SLC9A1 (0.46) SLC9A1
SCHEMBL8444435 0.78 HTR2B (0.39) SLC9A1
SCHEMBL8442629 0.77 CA12 (0.35) SLC9A1
SCHEMBL8440989 0.77 SLC9A1 (0.43) SLC9A1
SCHEMBL8440950 0.76 SLC9A1 (0.40) SLC9A1
SCHEMBL8439952 0.76 PMM2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968985-A INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-19 US disclosed
EP-0773927-A2 BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-21 EP disclosed
WO-1996004241-A2 BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed