Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443921 | 0.89 | HTR2B (0.39) | HTR2BSLC9A1PTPN1MEN1KMT2A | |
| SCHEMBL8444342 | 0.87 | HTR2B (0.37) | HTR2BCYP2C19SLC9A1PTPN1MEN1 | |
| SCHEMBL8802443 | 0.83 | HTR2B (0.56) | HTR2BCYP2C19SLC9A1 | |
| SCHEMBL8441028 | 0.78 | SLC9A1 (0.38) | HTR2BSLC9A1 | |
| SCHEMBL8444457 | 0.78 | DHODH (0.40) | SLC9A1CA2 | |
| SCHEMBL8440952 | 0.78 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8444497 | 0.77 | SLC9A1 (0.38) | HTR2BSLC9A1CA2 | |
| SCHEMBL7822730 | 0.76 | SLC9A1 (0.46) | SLC9A1MEN1KMT2ACA2 | |
| SCHEMBL8444433 | 0.76 | CYP2C19 (0.40) | CYP2C19SLC9A1PTPN1PTPN6MEN1 | |
| SCHEMBL8443930 | 0.76 | SLC9A1 (0.40) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |