Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196585 | 0.91 | ALOX5 (0.62) | ALOX5HDAC7FOLH1NAAANPC1 | |
| SCHEMBL8487740 | 0.91 | ALOX5 (0.67) | ALOX5HDAC7FOLH1NAAANPC1 | |
| SCHEMBL3441243 | 0.91 | ALOX5 (0.67) | ALOX5HDAC7FOLH1NAAANPC1 | |
| SCHEMBL7668122 | 0.87 | ALOX5 (0.64) | ALOX5HDAC7FOLH1NAAANPC1 | |
| SCHEMBL8488937 | 0.87 | ALOX5 (0.64) | ALOX5HDAC7FOLH1NAAANPC1 | |
| SCHEMBL8487702 | 0.84 | ALOX5 (0.54) | ALOX5NPC1ALDH1A1MAPTHPGD | |
| SCHEMBL8488000 | 0.84 | ALOX5 (0.54) | ALOX5NPC1ALDH1A1MAPTHPGD | |
| SCHEMBL8487544 | 0.82 | ALOX5 (0.70) | ALOX5HDAC7NAAANPC1ALDH1A1 | |
| SCHEMBL18196692 | 0.82 | FNTA (0.49) | ALOX5FOLH1NAAAALDH1A1 | |
| SCHEMBL7669752 | 0.81 | ALOX5 (0.59) | ALOX5HDAC7FOLH1NAAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907633-A1 | NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | Grünenthal GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049670-A1 | NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | Grünenthal GmbH (DE) | 1997-12-31 | — | — | WO | disclosed |