Curcumin

Curcumin

SCHEMBL8441

COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 1.00
MAPT P10636 9/20 1.00
BACE1 P56817 5/20 1.00
MMP9 P14780 4/20 1.00
NFKB1 P19838 3/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C9 P11712 2/20 1.00
TSHR P16473 2/20 1.00
HSD17B10 Q99714 2/20 1.00
ABCB1 P08183 2/20 1.00
AKR1B1 P15121 2/20 1.00
MAOA P21397 2/20 1.00
MAOB P27338 2/20 1.00
HDAC3 O15379 2/20 1.00
HDAC1 Q13547 2/20 1.00
HDAC2 Q92769 2/20 1.00
HDAC6 Q9UBN7 2/20 1.00
ALOX5 P09917 2/20 1.00
STAT3 P40763 2/20 1.00
NFKB2 Q00653 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Curcumin SCHEMBL29876635 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL2804734 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL29360171 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL17629819 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL250984 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL6901740 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL29358937 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL17629818 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL8336603 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1
Curcumin SCHEMBL8440 1.00 APP (1.00) APPMAPTBACE1MMP9NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 172077 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372265-B1 None US claimed
US-20260144750-A1 Dosing Regimens for Treatment of Glioblastoma SIGNPATH PHARMA INC. (US) 2026-05-28 US claimed
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-05-28 US claimed
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP claimed
EP-4746864-A1 C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION Keto Innovations, LLC (US) 2026-05-27 EP claimed
EP-4749288-A1 COMPOSITIONS FOR DETECTING, CHARACTERIZING, AND REMOVING A BIOFILM COSA Group GmbH (DE) 2026-05-27 EP claimed
EP-4747611-A1 OPTICAL ELECTRODE ANALYTE DETECTION SYSTEM AND METHODS OF USE Vital Biosciences Inc. (CA) 2026-05-27 EP claimed
CN-120210296-B Preparation process of nanoscale water-soluble squalene ANHUI TIANYIN BIOTECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121378801-B Photo-crosslinking double-network hydrogel for promoting skin wound healing and preparation method thereof Shandong second people's Hospital (Shandong ear nose throat hospital, Shandong ear nose throat Research Institute) (CN) 2026-05-26 CN claimed
CN-118141855-B Compound Chinese medicinal powder aerosol for treating respiratory tract infection and preparation method thereof Affiliated Hospital of Zunyi Medical University (CN) 2026-05-26 CN claimed
US-4263333-A REACTING TURMERIC WITH ZINC OR TIN IONS TO PRODUCE FOOD COLORING GENERAL FOODS CORPORATION (US) 1981-04-21 US claimed
US-4261879-A DENTISTRY JOHNSON & JOHNSON DENTAL PRODUCTS COMPANY (US) 1981-04-14 US claimed
EP-0025637-A1 Curcumin-metal colour complexes and process for preparing them GENERAL FOODS CORPORATION (US) 1981-03-25 EP claimed
US-4163803-A Turmeric coloring process and composition for foods and beverages GOLDSCHER KENNETH J 1979-08-07 US claimed
US-4154106-A COLORIMETRIC, THERMOSENSITIVE MORISHITA JINTAN COMPANY, LIMITED (JP) 1979-05-15 US claimed
US-4138212-A Process for producing water and oil soluble curcumin coloring agents STRANSKY CHARLES E 1979-02-06 US claimed
US-4069351-A HYDROPHILIC AND LIPOPHILIC FLAVOR AND ODOR COMPONENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-01-17 US claimed
US-4061786-A Dyed edible food casings NATURIN-WERK BECKER & CO. (DT) 1977-12-06 US claimed
US-3943262-A Process for the production of a dyed edible food casing NATURIN-WERK BECKER & CO. (DT) 1976-03-09 US claimed
US-3940504-A TURMERIC BAKER RESEARCH DEVELOPMENT SERVICE, INC. (US) 1976-02-24 US claimed