Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441161 | 0.84 | TBXA2R (0.52) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL8441437 | 0.84 | TBXA2R (0.52) | ALDH1A1POLBPKMHTTMAPT | |
| SCHEMBL8438050 | 0.84 | ALDH1A1 (0.59) | ALDH1A1POLBSMN1; SMN2PKMHTT | |
| SCHEMBL8440900 | 0.84 | ALDH1A1 (0.56) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL8442663 | 0.81 | KMT2A (0.53) | ALDH1A1PKMMAPTTBXA2RCYP19A1 | |
| SCHEMBL8439085 | 0.79 | TBXA2R (0.43) | KDM4EALDH1A1POLBPKMHTT | |
| SCHEMBL8442597 | 0.78 | TBXA2R (0.58) | KDM4ECYP3A4ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8441524 | 0.75 | TBXA2R (0.50) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL8441169 | 0.75 | ALDH1A1 (0.63) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL8440906 | 0.74 | ALDH1A1 (0.58) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |