Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442525 | 0.90 | TBXA2R (0.52) | ALDH1A1PKMSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL8437957 | 0.89 | MEN1 (0.54) | ALDH1A1CYP3A4HTTTSHRMAPT | |
| SCHEMBL8440583 | 0.87 | ALDH1A1 (0.56) | ALDH1A1PKMSMN1; SMN2HTTTSHR | |
| SCHEMBL8442976 | 0.87 | ALDH1A1 (0.48) | ALDH1A1PKMTSHRSGMS1ADAMTS4 | |
| SCHEMBL8441478 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTSGMS1ADAMTS4 | |
| SCHEMBL8438766 | 0.84 | LMNA (0.53) | ALDH1A1PKMSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL8437796 | 0.84 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2TBXA2RMEN1 | |
| SCHEMBL8441165 | 0.84 | KDM4E (0.59) | ALDH1A1PKMPOLBSMN1; SMN2KDM4E | |
| SCHEMBL8440909 | 0.81 | TBXAS1 (0.48) | TBXA2R | |
| SCHEMBL8443153 | 0.80 | MEP1B (0.47) | ALDH1A1PKMSMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |