Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441206 | 0.85 | MEN1 (0.54) | MAPTL3MBTL1GAARAB9ASMN1; SMN2 | |
| SCHEMBL8441127 | 0.83 | MEN1 (0.41) | MAPTL3MBTL1GAARAB9APPARG | |
| SCHEMBL8439695 | 0.80 | MEN1 (0.47) | MAPTL3MBTL1GAARAB9AMEN1 | |
| SCHEMBL8440239 | 0.79 | CYP2D6 (0.43) | MAPTLTA4HMEN1KMT2ATDP1 | |
| SCHEMBL8441520 | 0.77 | IDO1 (0.42) | MAOBMAPTL3MBTL1GAAMAOA | |
| SCHEMBL8441865 | 0.76 | MEN1 (0.40) | MAPTL3MBTL1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8439498 | 0.76 | MEN1 (0.52) | MAPTL3MBTL1GAARAB9AMEN1 | |
| SCHEMBL29032676 | 0.74 | LMNA (0.62) | MAOBMAPTL3MBTL1GAAMAOA | |
| SCHEMBL28699966 | 0.74 | LMNA (0.62) | MAOBMAPTL3MBTL1GAAMAOA | |
| SCHEMBL1929060 | 0.73 | NR4A2 (0.61) | MAOBRAB9ASMN1; SMN2PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |