Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441513 | 0.83 | MAOB (0.43) | MEN1KMT2AALDH1A1RECQLTDP1 | |
| SCHEMBL8440239 | 0.83 | CYP2D6 (0.43) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL13478430 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1RECQLTDP1 | |
| SCHEMBL8441206 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL8439695 | 0.80 | MEN1 (0.47) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL8441133 | 0.77 | IDO1 (0.45) | MEN1KMT2AALDH1A1RECQLTDP1 | |
| SCHEMBL8439498 | 0.76 | MEN1 (0.52) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL8437407 | 0.74 | MEN1 (0.39) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL8441865 | 0.74 | MEN1 (0.40) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL9224161 | 0.73 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1RECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |