Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPN | P05981 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12481966 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL8441582 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL1000596 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL2161104 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL2161085 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL9611222 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL9611224 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL15368932 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL15338715 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HPNPLAU | |
| SCHEMBL14193465 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1HPNPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |