Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HPN | P05981 | 2/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611224 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL8441582 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL12481966 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL2161085 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL1000596 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL2161104 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL4059194 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL13167998 | 0.83 | NPSR1 (0.53) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL15368932 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAAGLAMAPT | |
| SCHEMBL28736950 | 0.82 | SLC1A3 (0.49) | ALDH1A1GAAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136164-A1 | NANOSTRUCTURED METALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-05-31 | — | — | US | disclosed |
| US-20120136164-A1 | NANOSTRUCTURED METALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-05-31 | — | — | US | disclosed |
| WO-2010114490-A1 | NANOSTRUCTURED METALS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136164-A1 | NANOSTRUCTURED METALS | GNE, PIN1, HLA-C | ALDH1A1 416/4885KDM4E 3747/4885GAA 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.