Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.37 |
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440547 | 0.83 | NPSR1 (0.38) | MEN1KMT2AATMHTT | |
| SCHEMBL8380821 | 0.83 | PTAFR (0.33) | DRD3DRD2MEN1KMT2APOLB | |
| SCHEMBL8443545 | 0.82 | GALR3 (0.38) | MEN1KMT2APOLB | |
| SCHEMBL8439251 | 0.82 | KDM4E (0.39) | DRD2MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL8550349 | 0.80 | KDM4E (0.42) | MEN1KMT2APOLBHTT | |
| SCHEMBL8672723 | 0.80 | MEN1 (0.38) | PKMMEN1KMT2APOLBHTT | |
| SCHEMBL8443200 | 0.79 | KMT2A (0.42) | DRD3PKMMEN1KMT2APOLB | |
| SCHEMBL8669339 | 0.79 | MEN1 (0.39) | PKMMEN1KMT2APOLBHTT | |
| SCHEMBL8441755 | 0.79 | MEN1 (0.39) | DRD3DRD2DRD1PKMMEN1 | |
| Hydrochloric Acid SCHEMBL8860684 | 0.78 | MEN1 (0.38) | DRD3DRD2PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |