Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441758 | 0.83 | DRD3 (0.37) | DRD2DRD3HTTCYP2D6KMT2A | |
| SCHEMBL8380817 | 0.81 | MEN1 (0.34) | PTAFRDRD2DRD3ALDH1A1LMNA | |
| SCHEMBL8440547 | 0.79 | NPSR1 (0.38) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL8443545 | 0.78 | GALR3 (0.38) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8439251 | 0.78 | KDM4E (0.39) | DRD2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8443201 | 0.77 | TDP1 (0.44) | DRD2DRD3SMN1; SMN2CYP2D6 | |
| SCHEMBL8441860 | 0.76 | DRD2 (0.46) | DRD2DRD3CYP2D6 | |
| SCHEMBL8672723 | 0.76 | MEN1 (0.38) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL8443200 | 0.75 | KMT2A (0.42) | DRD3ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8669339 | 0.75 | MEN1 (0.39) | ALDH1A1LMNAHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | claimed |
| JP-5117268-A | — | — | None | — | — | JP | disclosed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |
| JP-H05117268-A | PYRIDINE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1993-05-14 | — | — | JP | disclosed |