Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669339 | 0.94 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8443200 | 0.88 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2LMNAHPGD | |
| SCHEMBL8550349 | 0.87 | KDM4E (0.42) | MEN1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8668968 | 0.84 | SMN1; SMN2 (0.39) | KMT2ASMN1; SMN2LMNAHPGDTP53 | |
| SCHEMBL5134227 | 0.83 | MAPT (0.51) | KMT2ALMNAHPGDPDE2APDE10A | |
| SCHEMBL8551897 | 0.83 | LMNA (0.35) | MEN1KMT2ASMN1; SMN2LMNATP53 | |
| SCHEMBL8672735 | 0.83 | MAPT (0.37) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL8443201 | 0.83 | TDP1 (0.44) | SMN1; SMN2PDE2AHSD17B10TSHR | |
| SCHEMBL8667814 | 0.82 | HTR2B (0.34) | MEN1KMT2ASMN1; SMN2KDM4EPKM | |
| SCHEMBL8668399 | 0.82 | ALDH1A1 (0.37) | KMT2ASMN1; SMN2LMNAHPGDPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |