SCHEMBL8442263

SCHEMBL8442263

CC1=C(c2c(C)cc(Cc3cc(C)c(C4=C(C)C(=O)NC4=O)c(C)c3)cc2C)C(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.33
CXCL12 P48061 1/20 0.33
SHBG P04278 1/20 0.32
PARP1 P09874 1/20 0.31
HTR2A P28223 2/20 0.31
HTR2C P28335 2/20 0.31
HTR2B P41595 2/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27235775 0.89 SHBG (0.34) SHBGHTR2AHTR2CHTR2B
SCHEMBL8441691 0.82 GSK3B (0.33) SHBG
SCHEMBL28530505 0.80 HTR2A (0.39) HTR2AHTR2CHTR2B
SCHEMBL8443716 0.79 PARP1 (0.33) PARP1
SCHEMBL28522380 0.76 FFAR4 (0.35) HTR2AHTR2CHTR2B
SCHEMBL3673282 0.75 DAO (0.41) HTR2AHTR2CHTR2B
SCHEMBL10586896 0.72 PTGS2 (0.41) TGM2
SCHEMBL23291852 0.70 CDK4 (0.30) PARP1
SCHEMBL996564 0.70 PTGS2 (0.33)
SCHEMBL23291869 0.69 KDM4E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415491-A Resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2019-03-01 CN disclosed
CN-109415489-A Resin combination, resin sheet, multilayer printed-wiring board and semiconductor device 三菱瓦斯化学株式会社 2019-03-01 CN disclosed
CN-109071745-A Cyanate ester compound, method for producing same, resin composition, cured product, prepreg, sealing material, fiber-reinforced composite material, adhesive, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2018-12-21 CN disclosed
EP-0495544-B1 Process for the synthesis of citraconimides AKZO NOBEL NV (NL) 1999-04-07 EP disclosed