Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445327 | 0.78 | GPR119 (0.48) | GPR119KDM4EPKMTSHR | |
| SCHEMBL15085741 | 0.74 | GPR119 (0.59) | HPGDGPR119FAAHKDM4EPKM | |
| SCHEMBL6953531 | 0.73 | ACHE (0.55) | ALDH1A1GPR119FAAHKDM4EPKM | |
| SCHEMBL5475624 | 0.72 | ACHE (0.53) | ALDH1A1GPR119FAAHKDM4EPKM | |
| SCHEMBL13913655 | 0.72 | KDM4E (0.60) | GPR119FAAHKDM4EPKMGAA | |
| SCHEMBL15594335 | 0.71 | MAPK1 (0.42) | ALDH1A1HPGDGPR119KDM4ETSHR | |
| SCHEMBL31596884 | 0.71 | GPR119 (0.53) | ALDH1A1HPGDGPR119FAAHKDM4E | |
| SCHEMBL9155598 | 0.71 | TSHR (0.57) | ALDH1A1HPGDGAATSHR | |
| SCHEMBL3358948 | 0.71 | KDM4E (0.59) | ALDH1A1GPR119FAAHKDM4EPKM | |
| SCHEMBL5670690 | 0.71 | PARP1 (0.55) | ALDH1A1HPGDGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |