Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772506 | 0.81 | KMT2A (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8440478 | 0.78 | ALDH1A1 (0.41) | FDFT1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8440760 | 0.77 | SMN1; SMN2 (0.39) | KMT2ASMN1; SMN2ALDH1A1HTTHSP90AA1 | |
| Acetic Acid SCHEMBL29697257 | 0.66 | CA1 (0.73) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL481332 | 0.65 | CA1 (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL128190 | 0.65 | CA1 (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| Benzene SCHEMBL27873122 | 0.64 | CA1 (0.76) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL87450 | 0.64 | CA1 (0.83) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL10669311 | 0.64 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31421740 | 0.64 | CA1 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915843-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES | SMITHKLINE BEECHAM PLC (GB) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997041098-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-06 | — | — | WO | disclosed |