Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442117 | 0.84 | MKNK1 (0.48) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL8309933 | 0.84 | PPARA (0.48) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL8309932 | 0.84 | PPARA (0.48) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL5610798 | 0.84 | LMNA (0.56) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL5610797 | 0.84 | LMNA (0.56) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL5609892 | 0.83 | LMNA (0.65) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL5609899 | 0.83 | LMNA (0.65) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL8304869 | 0.82 | PPARG (0.52) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL8304871 | 0.82 | PPARG (0.52) | LMNASMN1; SMN2PTBP1MAPK1HTT | |
| SCHEMBL5609817 | 0.81 | PPARG (0.50) | LMNASMN1; SMN2PTBP1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972959-A | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0708098-B1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |