Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.47 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | DDT | P30046 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550173 | 0.83 | GSK3B (0.51) | KMOKEAP1NPC1POLBMAOB | |
| SCHEMBL8443258 | 0.83 | AXL (0.49) | NPC1POLBAXLGSK3BPIN1 | |
| SCHEMBL11550178 | 0.83 | SMN1; SMN2 (0.48) | KMOKEAP1NPC1POLBRXRA | |
| SCHEMBL11458495 | 0.83 | GSK3B (0.56) | NPC1POLBMAP2K4MIFMAOB | |
| SCHEMBL8802708 | 0.82 | KEAP1 (0.53) | KMOKEAP1POLBAXLRXRA | |
| SCHEMBL11623160 | 0.81 | PIN1 (0.55) | KMONPC1POLBMAPK1TTR | |
| SCHEMBL11620715 | 0.81 | POLB (0.59) | KMONPC1POLBTTRGSK3B | |
| SCHEMBL21310963 | 0.78 | KDM4C (0.54) | KMOMAOBIKBKETBK1 | |
| SCHEMBL23972419 | 0.78 | PLA2G10 (0.48) | NPC1POLBMIF | |
| SCHEMBL1310425 | 0.78 | PIN1 (0.56) | NPC1POLBMAPK1MIFMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |
| US-4212865-A | BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4190590-A | DISINFECTING AND STERILIZING DENTAL AND MEDICAL EQUIPMENT | RIKER LABORATORIES, INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4124602-A | OPTIONALLY SUBSTITUTED 3-(CYANOPHENYL)BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4048323-A | Antimicrobial (2-nitro-3-benzofuranyl)-benzoic acids | RIKER LABORATORIES, INC. (US) | 1977-09-13 | — | — | US | disclosed |