Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439394 | 0.80 | DGAT1 (0.43) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL237417 | 0.79 | CYP1A2 (0.55) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL759906 | 0.77 | CYP1A2 (0.59) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL237019 | 0.71 | CYP1A2 (0.55) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10627775 | 0.71 | NPC1 (0.74) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2755212 | 0.68 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL236593 | 0.68 | NPC1 (0.56) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL2755218 | 0.67 | NPC1 (0.46) | PKMNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL238840 | 0.67 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL2755213 | 0.67 | RAB9A (0.83) | NPC1RAB9ASMN1; SMN2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856320-A | ANTIBIOTIC RESISTANT STAPYLOCOCCUS | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0771803-A1 | Pyrazolo(1,5-a)pyrimidinium substituted cephem derivatives, their preparation and their use as antimicrobial agents | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |