Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.35 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441632 | 0.88 | BCAT2 (0.37) | HTR1AADORA3CCKARHTR5ASLC9A1 | |
| SCHEMBL8441543 | 0.85 | SLC9A1 (0.34) | CA12CA1CA2CA9HTR1A | |
| SCHEMBL7830864 | 0.85 | SLC9A1 (0.34) | CA12CA1CA2CA9HTR1A | |
| SCHEMBL8440989 | 0.84 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL8804547 | 0.83 | HTR2B (0.43) | SLC9A1 | |
| SCHEMBL8442896 | 0.81 | CDK5 (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL8440927 | 0.80 | HDAC2 (0.46) | SLC9A1 | |
| SCHEMBL8440628 | 0.79 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL7822730 | 0.78 | SLC9A1 (0.46) | CA12CA1CA2CA9ADORA3 | |
| SCHEMBL8444457 | 0.78 | DHODH (0.40) | CA12CA1CA2CA9SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |