Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21451658 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD11B1 | |
| SCHEMBL19276475 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD11B1 | |
| SCHEMBL8442842 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2 | |
| SCHEMBL8436912 | 0.72 | KDM4E (0.46) | SMN1; SMN2 | |
| SCHEMBL8436838 | 0.71 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL8443208 | 0.69 | ALDH1A1 (0.47) | SMN1; SMN2 | |
| SCHEMBL12524480 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2HSD11B1 | |
| SCHEMBL8261375 | 0.68 | ATM (0.39) | — | |
| SCHEMBL22952310 | 0.65 | — | — | |
| SCHEMBL1527324 | 0.65 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329658-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER INC (US) | 2008-02-12 | — | — | US | disclosed |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20040157839-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157839-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | SMN1; SMN2 3678/4885HSD11B1 2171/4885 |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | SMN1; SMN2 3902/4885HSD11B1 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.