Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 14/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443424 | 0.86 | SLC9A1 (0.33) | SLC9A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7816360 | 0.85 | SLC9A1 (0.34) | SLC9A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8444497 | 0.84 | SLC9A1 (0.38) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL7822730 | 0.82 | SLC9A1 (0.46) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL8440628 | 0.81 | SLC9A1 (0.40) | SLC9A1 | |
| SCHEMBL8803822 | 0.81 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL7824600 | 0.80 | HDAC2 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL8443921 | 0.78 | HTR2B (0.39) | SLC9A1 | |
| SCHEMBL8444457 | 0.78 | DHODH (0.40) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL8442629 | 0.78 | CA12 (0.35) | SLC9A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |