Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 12/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444375 | 0.84 | SLC9A1 (0.36) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL8441028 | 0.83 | SLC9A1 (0.38) | SLC9A1HTR2B | |
| SCHEMBL8443424 | 0.82 | SLC9A1 (0.33) | SLC9A1F2F10CA12CA1 | |
| SCHEMBL7816360 | 0.81 | SLC9A1 (0.34) | SLC9A1F2F10CA12CA1 | |
| SCHEMBL8440595 | 0.81 | ASH1L (0.52) | SLC9A1PRKCI | |
| SCHEMBL8440989 | 0.80 | SLC9A1 (0.43) | SLC9A1 | |
| SCHEMBL7824600 | 0.78 | HDAC2 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL8444435 | 0.77 | HTR2B (0.39) | SLC9A1CA2HTR2B | |
| SCHEMBL8443921 | 0.77 | HTR2B (0.39) | SLC9A1HTR2B | |
| SCHEMBL7822730 | 0.76 | SLC9A1 (0.46) | SLC9A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |