Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388535 | 0.90 | EPHX2 (0.39) | EPHX2TSHRNPSR1BRD4GAA | |
| SCHEMBL31459648 | 0.87 | EPHX2 (0.36) | EPHX2TSHRBRD4GAAHSD17B10 | |
| SCHEMBL18517008 | 0.86 | EPHX2 (0.39) | EPHX2TSHRNPSR1BRD4GAA | |
| SCHEMBL11068018 | 0.86 | EPHX2 (0.39) | EPHX2TSHRNPSR1BRD4GAA | |
| Hydrochloric Acid SCHEMBL28795083 | 0.84 | EPHX2 (0.38) | EPHX2TSHRNPSR1BRD4SMN1; SMN2 | |
| SCHEMBL8891785 | 0.84 | SLC6A2 (0.38) | EPHX2TSHRNPSR1BRD4SMN1; SMN2 | |
| SCHEMBL13895147 | 0.84 | EPHX2 (0.38) | EPHX2TSHRNPSR1BRD4GAA | |
| SCHEMBL12616310 | 0.83 | ALDH1A1 (0.38) | EPHX2TSHRBRD4GAAHSD17B10 | |
| SCHEMBL10389690 | 0.82 | CYP2D6 (0.40) | EPHX2TSHRNPSR1BRD4GAA | |
| SCHEMBL18517048 | 0.82 | EPHX2 (0.37) | EPHX2TSHRNPSR1BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724260-A1 | Process for the synthesis of ¬2S, 3aR, 7aS|-octahydroindole-2-carboxylic acid and its conversion to trandolapril | Sochinaz SA (CH) | 2006-11-22 | — | — | EP | disclosed |