Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895126 | 0.96 | HCRTR1 (0.34) | EPHX2TSHRBRD4NPSR1ALDH1A1 | |
| SCHEMBL8444550 | 0.84 | EPHX2 (0.44) | EPHX2TSHRBRD4NPSR1POLB | |
| SCHEMBL13867649 | 0.83 | EPHX2 (0.41) | EPHX2NPSR1ALDH1A1L3MBTL1HCRTR1 | |
| SCHEMBL9056296 | 0.82 | EPHX2 (0.41) | EPHX2TSHRALDH1A1HSD17B10 | |
| SCHEMBL14429810 | 0.81 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL10145351 | 0.77 | SLC6A12 (0.39) | L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL26897449 | 0.76 | SMN1; SMN2 (0.33) | ALDH1A1CYP2C19GAA | |
| SCHEMBL3826823 | 0.76 | EPHX1 (0.43) | EPHX2L3MBTL1GAA | |
| SCHEMBL18517008 | 0.76 | EPHX2 (0.39) | EPHX2TSHRBRD4NPSR1ALDH1A1 | |
| SCHEMBL28388535 | 0.76 | EPHX2 (0.39) | EPHX2TSHRBRD4NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524852-B2 | Bicyclic pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |