Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8444562 | 0.75 | CYP1A2 (0.55) | CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8446163 | 0.74 | QPCT (0.52) | CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11630824 | 0.71 | CYP19A1 (0.53) | — | |
| SCHEMBL11752398 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11748473 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11750323 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11754069 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11752382 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11752673 | 0.68 | TBXAS1 (0.48) | CYP3A4CYP1A2CYP2C9TBXAS1SMN1; SMN2 | |
| SCHEMBL11487555 | 0.68 | CYP19A1 (0.49) | CYP3A4CYP2D6CYP1A2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |