SCHEMBL8444804

SCHEMBL8444804

C[C]1CC(C)CCC1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TRPA1 O75762 2/20 0.31
TRPM8 Q7Z2W7 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697828 0.76 TRPA1 (0.35) NPC1L3MBTL1TRPA1TRPM8
Menthone SCHEMBL21709 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8
Menthone SCHEMBL901274 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8
SCHEMBL6248974 0.74 TRPA1 (0.30) NPC1L3MBTL1TRPA1TRPM8
Menthone SCHEMBL13255148 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8
SCHEMBL23332079 0.74 NOS3 (0.31) NPC1L3MBTL1TRPA1TRPM8
Rel-Menthone SCHEMBL21711 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8
Menthone SCHEMBL4395963 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8
SCHEMBL2121390 0.74 NOS3 (0.35) NPC1L3MBTL1TRPA1TRPM8
Rel-Menthone SCHEMBL1868327 0.74 TLR4 (0.39) NPC1L3MBTL1TRPA1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108882737-A Emulsification composition and powder composition 长谷川香料株式会社 2018-11-23 CN disclosed
US-5897857-A SULFHYDRYL COMPOUND SELECTED FROM CYSTEINE, HOMOCYCTEINE, GLUTATHIONE, THIOGLYCEROL, THIOMALIC ACID, 2-MERCAPTOETHANOL, MERCAPTOPROPIONIC ACIDS, DITHIOTHREITOL, THIOSALICYLIC ACID, N-ACETYL-L-CYSTEIN AND SALTS; FACIAL HAIR REMOVER THE PROCTER & GAMBLE COMPANY (US) 1999-04-27 US disclosed
EP-0228064-B1 PHOTOGRAPHIC ELEMENTS WITH STERICALLY HINDERED PHOTOGRAPHIC COUPLER SOLVENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-03-14 EP disclosed
US-4827019-A SOLVENTS FOR COUPLERS IN COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1989-05-02 US disclosed
US-4684606-A PROTECTION OF CYAN DYE AGAINST FERROUS ION REDUCTION EASTMAN KODAK COMPANY (US) 1987-08-04 US disclosed
EP-0228064-A2 Photographic elements with sterically hindered photographic coupler solvents EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-07-08 EP disclosed