Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13505488 | 0.87 | — | — | |
| SCHEMBL8473361 | 0.84 | BRD4 (0.37) | BRD4 | |
| SCHEMBL8469866 | 0.84 | BRD4 (0.50) | BRD4 | |
| SCHEMBL13745854 | 0.84 | GSK3B (0.43) | BRD4 | |
| SCHEMBL3347141 | 0.82 | HTR6 (0.38) | BRD4 | |
| SCHEMBL13746452 | 0.77 | ACVR1 (0.42) | BRD4 | |
| SCHEMBL13505455 | 0.73 | MAPT (0.32) | — | |
| SCHEMBL14031165 | 0.73 | PFKFB3 (0.35) | BRD4 | |
| SCHEMBL13539016 | 0.70 | PLK4 (0.34) | — | |
| SCHEMBL13505483 | 0.70 | KCNH2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749829-B1 | JNK inhibitors | EISAI R&D MAN CO LTD (JP) | 2010-11-03 | — | — | EP | disclosed |
| EP-1749829-A1 | JNK inhibitors | Eisai London Research Laboratories Limited (GB) | 2007-02-07 | — | — | EP | disclosed |