Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408674 | 0.87 | MAPT (0.50) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL11408692 | 0.84 | TSHR (0.47) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL18814844 | 0.83 | TSHR (0.49) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL2777612 | 0.81 | PDE7A (0.55) | TSHRTDP1PDE7AALDH1A1MAPK1 | |
| SCHEMBL8446725 | 0.81 | TSHR (0.58) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL8446872 | 0.81 | ALDH1A1 (0.58) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL17498318 | 0.80 | TDP1 (0.62) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL11409450 | 0.78 | GSTP1 (0.54) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL11413362 | 0.77 | TSHR (0.53) | TSHRTDP1PDE7AALDH1A1CYP3A4 | |
| SCHEMBL2765848 | 0.75 | TSHR (0.60) | TSHRTDP1PDE7AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | claimed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | claimed |
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | disclosed |
| US-5542952-A | DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES | L'OREAL (FR) | 1996-08-06 | — | — | US | disclosed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | disclosed |
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |