Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408674 | 0.91 | MAPT (0.50) | TSHRTDP1ALDH1A1CYP3A4RECQL | |
| SCHEMBL8445197 | 0.84 | TSHR (0.53) | TSHRTDP1ALDH1A1CYP3A4RECQL | |
| SCHEMBL15155306 | 0.82 | CA2 (0.44) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8446872 | 0.82 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1CYP3A4RECQL | |
| SCHEMBL17538418 | 0.80 | MAPT (0.58) | TSHRTDP1ALDH1A1CYP3A4RECQL | |
| SCHEMBL8973221 | 0.78 | PTGS2 (0.49) | TDP1ALDH1A1PDE7ACA2HSD17B10 | |
| SCHEMBL18814844 | 0.78 | TSHR (0.49) | TSHRTDP1ALDH1A1CYP3A4RECQL | |
| SCHEMBL8347178 | 0.78 | MAPT (0.41) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10660283 | 0.77 | TLR8 (0.47) | TSHRALDH1A1L3MBTL1MAPTTLR8 | |
| SCHEMBL7746689 | 0.77 | PDE7A (0.47) | TSHRTDP1ALDH1A1PDE7AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |