Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCND2 | P30279 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442411 | 0.93 | TMEM97 (0.47) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8443521 | 0.93 | DRD2 (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8445196 | 0.88 | SCN7A (0.43) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL8445171 | 0.86 | NPY1R (0.49) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL28404370 | 0.84 | KDM4E (0.59) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL31033172 | 0.84 | SCN7A (0.56) | KDM4EALDH1A1SCN7A | |
| SCHEMBL8442952 | 0.81 | TMEM97 (0.44) | — | |
| SCHEMBL708145 | 0.79 | CA12 (0.41) | SCN7ACNR1CNR2HTR7 | |
| SCHEMBL8445200 | 0.77 | KDM4E (0.37) | KDM4EALDH1A1NPSR1HSD17B10CDK4 | |
| SCHEMBL12124540 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |