Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCND2 | P30279 | 1/20 | 0.41 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442411 | 0.88 | TMEM97 (0.47) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8443521 | 0.88 | DRD2 (0.48) | OPRM1OPRL1OPRK1 | |
| SCHEMBL8445198 | 0.86 | OPRM1 (0.47) | OPRM1OPRL1OPRK1CDK4CCND1 | |
| SCHEMBL8442952 | 0.84 | TMEM97 (0.44) | — | |
| SCHEMBL8445196 | 0.81 | SCN7A (0.43) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL4090351 | 0.81 | CHRM1 (0.53) | NPY1R | |
| SCHEMBL28404370 | 0.80 | KDM4E (0.59) | OPRM1OPRL1OPRK1CDK4CCND1 | |
| SCHEMBL8443137 | 0.78 | NPY1R (0.47) | NPY1RHPGD | |
| SCHEMBL8442501 | 0.77 | MCHR1 (0.45) | NPY1RALDH1A1 | |
| SCHEMBL8442954 | 0.74 | DRD2 (0.36) | KDM4EALDH1A1NPSR1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |