Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 9/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561441 | 0.93 | LIPG (0.46) | LPLLIPGMAOAMAOBCA1 | |
| SCHEMBL2801619 | 0.90 | LPL (0.51) | LPLLIPGMAOBTSHR | |
| SCHEMBL18124821 | 0.90 | LIPG (0.50) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL4602862 | 0.87 | LPL (0.49) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL13453433 | 0.87 | LPL (0.59) | LPLLIPGTSHR | |
| SCHEMBL23078522 | 0.86 | LIPG (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL31150275 | 0.86 | LPL (0.48) | LPLLIPGMAOBTSHR | |
| SCHEMBL1830523 | 0.86 | LPL (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL2979968 | 0.86 | LPL (0.48) | LPLLIPGCA1CA2CA9 | |
| SCHEMBL4513327 | 0.85 | LPL (0.47) | LPLLIPGCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021043116-A1 | BIPHENYL COMPOUNDS, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |
| EP-2196465-A1 | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |