Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 16/20 | 0.74 |
| ▸ | CHRM4 | P08173 | 16/20 | 0.74 |
| ▸ | CHRM5 | P08912 | 16/20 | 0.74 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.74 |
| ▸ | DRD2 | P14416 | 12/20 | 0.74 |
| ▸ | DRD4 | P21917 | 12/20 | 0.74 |
| ▸ | DRD3 | P35462 | 12/20 | 0.74 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.71 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601865 | 0.93 | CHRM2 (0.71) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8442782 | 0.92 | CHRM2 (0.69) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8443011 | 0.91 | CHRM1 (0.68) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8443141 | 0.91 | CHRM2 (0.68) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8442415 | 0.91 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8442789 | 0.89 | CHRM1 (0.64) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8445194 | 0.89 | CHRM2 (0.64) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8445380 | 0.85 | CHRM2 (0.68) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL12013902 | 0.82 | ACHE (0.75) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL29400334 | 0.82 | CHRM2 (1.00) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |