Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072327 | 0.80 | ACHE (0.56) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL12245 | 0.80 | ACHE (0.56) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL13330969 | 0.80 | CHRM2 (0.44) | ALDH1A1L3MBTL1MAPK1TDP1CETP | |
| SCHEMBL12853903 | 0.79 | ACHE (0.50) | ACHELMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL5549887 | 0.79 | ACHE (0.54) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL20752042 | 0.79 | ACHE (0.54) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL8460171 | 0.79 | ACHE (0.54) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL9910049 | 0.78 | LTA4H (0.39) | L3MBTL1MAPK1 | |
| SCHEMBL5549913 | 0.77 | ACHE (0.52) | ACHELMNAARALDH1A1L3MBTL1 | |
| SCHEMBL19375277 | 0.77 | ACHE (0.52) | ACHELMNAARALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011722-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2021-01-21 | — | — | WO | disclosed |
| EP-2138498-A1 | Substituted tricyclic derivatives against neurodegenerative diseases | sanofi-aventis (FR) | 2009-12-30 | — | — | EP | disclosed |