Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445350 | 0.86 | ADK (0.42) | ADKUSP2PNPTSHREDNRA | |
| SCHEMBL8445449 | 0.86 | ADK (0.44) | ADKUSP2PNPTSHREDNRA | |
| SCHEMBL8444992 | 0.86 | SRC (0.46) | ADKUSP2PNPTSHREDNRA | |
| SCHEMBL17406926 | 0.83 | ADK (0.41) | ADKUSP2PNPTSHREDNRA | |
| SCHEMBL10388756 | 0.82 | TSHR (0.40) | ADKTSHRMEN1KMT2AKDM4E | |
| SCHEMBL10388919 | 0.79 | ADK (0.31) | ADKSRCLCKTEKMEN1 | |
| SCHEMBL10563489 | 0.75 | FDPS (0.50) | USP2PNPTSHREDNRAHTR2A | |
| SCHEMBL22524404 | 0.73 | ADK (0.39) | ADKSRCMEN1KMT2ANR2F2 | |
| SCHEMBL8441851 | 0.72 | DYRK3 (0.54) | ADKUSP2PNPTSHREDNRA | |
| SCHEMBL8442394 | 0.72 | SRC (0.46) | ADKUSP2PNPTSHREDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36187-E | HERPES SIMPLEX VIRUS; HUMAN CYTOMEGALOVIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-04-06 | — | — | US | disclosed |
| US-4968686-A | DECREASED CYTOTOXICITY; CYTOMEGALO AND HERPEX SIMPLEX VIRUSES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-11-06 | — | — | US | disclosed |
| US-4927830-A | HERPES, CYTOMEGALO VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-05-22 | — | — | US | disclosed |