Stearic Acid

Stearic Acid

SCHEMBL8445561

CCCCCCCCCCCCCCCCCC(=O)O.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.68

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Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.68
PPARG P37231 7/20 0.68
PPARD Q03181 7/20 0.68
PPARA Q07869 7/20 0.68
HDAC11 Q96DB2 5/20 0.68
TSHR P16473 5/20 0.68
PTPN1 P18031 3/20 0.68
ALDH1A1 P00352 2/20 0.68
TLR2 O60603 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
FABP4 P15090 2/20 0.68
KMT2A Q03164 2/20 0.68
SLC22A6 Q4U2R8 1/20 0.68
SLC22A8 Q8TCC7 1/20 0.68
MEN1 O00255 1/20 0.68
ESR1 P03372 1/20 0.68
ALOX15 P16050 1/20 0.68
PDE4A P27815 1/20 0.68
PDE3A Q14432 1/20 0.68
HSD17B10 Q99714 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Behenic Acid SCHEMBL22655274 1.00 GPR84 (0.68) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL28026106 0.98 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL8446001 0.98 GPR84 (0.65) GPR84PPARGPPARDPPARAHDAC11
Terephthalic Acid SCHEMBL28102303 0.98 AKR1B1 (0.67) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL10772857 0.96 GPR84 (0.63) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL1615180 0.93 HSD17B3 (0.67) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL27646266 0.93 HSD17B3 (0.67) GPR84PPARGPPARDPPARAHDAC11
Octanoic Acid SCHEMBL6051069 0.92 CES2 (0.64) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL23588 0.92 CES2 (0.64) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL10943211 0.92 CES2 (0.64) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417856-A Thermoreversibly discoloration core-shell polymers emulsion of stabilization with hysteresis effect and preparation method thereof 湖北大学 2017-12-01 CN claimed
CN-116794857-A Display panel, assembly method thereof, manufacturing method of display panel and electronic equipment 惠科股份有限公司 2023-09-22 CN disclosed
CN-107417856-B Stable thermoreversible color-changing core-shell polymer emulsion with hysteresis effect and preparation method thereof 湖北大学 2020-01-14 CN disclosed
CN-108559239-A A kind of high-temperature resistance plastice material 徐州通用高新磁电有限公司 2018-09-21 CN disclosed
CN-107417856-A Thermoreversibly discoloration core-shell polymers emulsion of stabilization with hysteresis effect and preparation method thereof 湖北大学 2017-12-01 CN disclosed
EP-0625564-B1 Lubricating oil INDIAN OIL CORP LTD (IN) 1999-01-13 EP disclosed
US-5387351-A Titanium alkoxide, carboxylic acid other than fatty acid, fatty acid, water in mineral or synthetic oil base INDIAN OIL CORPORATION (IN) 1995-02-07 US disclosed
EP-0625564-A1 Lubricating oil INDIAN OIL CORPORATION Ltd. (IN) 1994-11-23 EP disclosed